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Srpski arhiv za celokupno lekarstvo 2020 Volume 148, Issue 7-8, Pages: 489-492
https://doi.org/10.2298/SARH191202043S
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Tumors of the orbit as a first manifestation of a lung and breast malignancy

Stjepanović Mihailo ORCID iD icon (Clinical Center of Serbia, Clinic of pulmonology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, Serbia)
Marić Nikola (Clinical Center of Serbia, Clinic of pulmonology, Belgrade, Serbia)
Baralić Marko ORCID iD icon (Clinical Center of Serbia, Clinic of nephrology, Belgrade, Serbia)
Marić-Živković Jasmina (Clinical Center of Serbia, Clinic of pulmonology, Belgrade, Serbia)
Mihailović-Vučinić Violeta (Clinical Center of Serbia, Clinic of pulmonology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, Serbia)

Introduction. Orbit is one of the rarer locations for the metastasis of malignant tumors. The symptoms of orbital tumors are nonspecific, but require detail diagnostics. Methods of visualization, such as ultrasound, radiography, computed tomography scan and/or magnetic resonance imaging of the endocranium are a mandatory step in the diagnostics in order to determine not only the spread of the malignancy but also the affliction of the surrounding structures. The orbital manifestations can be the first sign of the malignant disease. Outline of cases. The first case report presents a female patient with ocular symptomatology as a result of a metastasis of previously undiscovered breast cancer, and the second report presents a male patient with undiscovered lung cancer also presenting with ocular symptomatology. Conclusion. An orbital tumor should instigate further diagnostic procedures, as it can be the first sign of a disseminated malignant disease.

Keywords: orbit, cancer, metastasis, lungs, breast

Projects of the Serbian Ministry of Education, Science and Technological Development, Grant no.175046 and Grant no.175081