doiSerbia

Large myomas as a complicating factor necessitating cesarean myomectomy followed by cesarean hysterectomy

Sparić Radmila (Clinical Centre of Serbia, Clinic for Gynecology and Obstetrics, Belgrade + School of Medicine, Belgrade)
Radunović Nebojša (Clinical Centre of Serbia, Clinic for Gynecology and Obstetrics, Belgrade + School of Medicine, Belgrade + Serbian Academy of Sciences and Arts, Belgrade)
Tinelli Andrea (Moscow Institute of Physics and Technology (State University), Department of Applied Mathematics, The International Translational Medicine and Biomodelling Research Group, Moscow, Russia + Vito Fazzi Hospital, Department of Obstetrics and Gynecology, Divi)
Radević Olivera (School of Medicine, Belgrade)
Kadija Saša (School of Medicine, Belgrade)

Introduction. Although uterine myomas are becoming more common in pregnancies due to advanced maternal age, the literature lacks reports on complications, such as hysterectomy following cesarean myomectomy (CM). The aim of this work was to describe when CM is inevitable, complicated by severe intrapartum hemorrhage and requiring a hysterectomy. Case outline. A pregnant, with a term pregnancy and large multiple myomas, was referred for elective cesarean section (CS). During the CS, forced enucleation of a 100 mm anterior and left myoma previa (pre-fetal extraction) was necessary, and a 2,800 g neonate was delivered through the lower uterine segment incision. After the delivery and another CM, it was necessary to stop a massive hemorrhage from the myometrial myoma bed. Following provisory suturings of the hysterotomies, an urgent hysterectomy was performed with left salpingo-oophorectomy, due to a large hematoma in the left retroperitoneal space. The patient’s further recovery was uneventful and she was discharged with her baby on the sixth postoperative day. The histopathology report revealed a 135 × 190 × 150 mm uterus, weighing together with the enucleated myomas and left adnexa 5,000 g in total. The weight of the enucleated myomas was 1,670 g. The histopathological examination also showed 12 intramural and subserous myomas in the myometrium, ranging 30–190 mm. Conclusion. Large myomas, especially previa, may present a serious problem for fetal extraction during a CS. Therefore, the authors suggest an informed consent for CM, in patients who should undergo a CS. Additionally, such patients should be counseled about the possibility of an intrapartum hysterectomy.

Keywords: myoma, pregnancy, complication, delivery