doiSerbia

Epithelioid hemangioma in the oral mucosa: A case report

Henriques Aguida Cristina Gomes (Federal University of Bahia, School of Dentistry, Laboratory of Surgical Pathology, Salvador, Bahia, Brazil)
Vidal Manuela Torres Andion (Federal University of Bahia, Department of Dentistry, Salvador, Bahia, Brazil)
Gurgel Clarissa Araujo (Federal University of Bahia, School of Dentistry, Laboratory of Surgical Pathology, Salvador, Bahia, Brazil)
Rocha Sanyra Lopes Dias (Federal University of Bahia, School of Dentistry, Salvador, Bahia, Brazil)
Carneiro Braulio Junior (State University of Southwestern Bahia, School of Dentistry, Division of Oral and Maxillofacial Surgery, Jequie, Bahia, Brazil)
Almeida de Azevedo Roberto (Federal University of Bahia, School of Dentistry, Division of Oral and Maxillofacial Surgery, Salvador, Bahia, Brazil)
dos Santos Jean Nunes (Federal University of Bahia, School of Dentistry, Laboratory of Surgical Pathology, Salvador, Bahia, Brazil)

Introduction. Epithelioid hemangioma is an uncommon benign vasoproliferative neoplasm that usually manifests as multiple red nodules in middle-aged adults. Case Outline. A 52-year-old male patient presented with a one-year history of a nodular lesion in the left buccal mucosa measuring 3 cm. The clinical hypothesis was lipoma. An excisional biopsy revealed a circumscribed lesion composed of lobules of vessels with perceptible or poor lumina, associated with a prominent inflammatory infiltrate consisting of eosinophils, histiocytes and chronic inflammatory cells. The endothelial cells composing the lesion had an epithelioid morphology and contained abundant eosinophilic cytoplasm. Immunohistochemistry for CD34, factor VIII, collagen IV, alpha-smooth muscle actin, and mast cells, as well as histochemical staining with Weigert’s orcein were performed. Conclusion. Vascular proliferations of soft tissues are a diverse and morphologically complex group of lesions that are difficult to diagnose. This report presents a case of oral epithelioid hemangioma, highlighting relevant morphological and immunohistochemical features that could help distinguish this condition from other neoplasms.

Keywords: angiolymphoid hyperplasia with eosinophilia, epithelioid hemangioma, oral mucosa