Srpski arhiv za celokupno lekarstvo 2016 Volume 144, Issue 9-10, Pages: 531-534
https://doi.org/10.2298/SARH1610531K
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Central mucoepidermoid carcinoma of the mandible: A case report
Krasić Dragan 
(Faculty of Medicine, Niš + Clinic of Dentistry, Niš)
Trajković Miloš (Clinic of Dentistry, Niš)
Mihailović Dragan (Faculty of Medicine, Niš + Institute for Pathology, Niš)
Krasić Staša (School of Medicine, Belgrade)
Živković Igor (Faculty of Medicine, Niš)
Spasić Milan (Clinic of Dentistry, Niš)
Živković Nikola (Faculty of Medicine, Niš + Institute for Pathology, Niš)
Introduction. Mucoepidermoid carcinoma, compared to other tumors of salivary
glands, occurs in 5-10% of cases. Histopathologically, it is divided into a
well differentiated tumor that is of low-grade of malignancy, and a medium
and poorly differentiated tumor of high grade of malignancy. Central
mucoepidermoid carcinoma (CMEC) of the mandible was firstly described by Lepp
in 1936, on a 66-year-old female patient. CMEC is characterized by atypical
clinical image and radiological manifestation. Case Outline. A 55-year-old
female patient was examined at the Clinic of Dentistry in Niš, Serbia, with
anamnestic data regarding the presence of painless swelling in the right side
of the mandible. Considering the histopathological results and presence of
enlarged lymph nodes, right hemimandibulectomy and tumour excision from
pterygomandibular space followed by supraomohyoid neck dissection was done.
In due course, postoperative radiotherapy was applied (60 Gy). Conclusion.
CMEC represents a rare tumor, characterized by local tissue destruction and
ability to metastasize. Initial biopsy represented the key in preoperative
planing. Radical excision with neck lymph node dissection followed by
postoperative radiotherapy in our case represent a successful method of
treating CMEC of the mandible.
Keywords: central carcinoma, mandibular swelling, biopsy, surgical therapy