Srpski arhiv za celokupno lekarstvo 2015 Volume 143, Issue 11-12, Pages: 676-680
https://doi.org/10.2298/SARH1512676B
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The burden of gastroesophageal reflux disease on patients’ daily lives: A cross-sectional study conducted in a primary care setting in Serbia
Bjelović Miloš (School of Medicine, Belgrade + Clinical Center of Serbia, First Surgical Clinic, Clinic for Digestive Surgery, Department for Minimally Invasive Upper Digestive Surgery, Belgrade)
Babič Tamara (Clinical Center of Serbia, First Surgical Clinic, Clinic for Digestive Surgery, Department for Minimally Invasive Upper Digestive Surgery, Belgrade)
Dragičević Igor (Public Health Institute, Šabac)
Ćorac Aleksandar (School of Medicine, Kosovska Mitrovica)
Trajković Goran (School of Medicine, Belgrade)
Introduction. Recent data from the studies conducted in the Western countries
have proved that patients with gastroesophageal reflux disease have
significantly impaired health-related quality of life compared to general
population. Objective. The study is aimed at evaluating the burden of reflux
symptoms on patients’ health-related quality of life. Methods. The study
involved 1,593 patients with diagnosed gastroesophageal reflux disease. The
Serbian version of a generic self-administered Centers for Disease Control
and Prevention questionnaire was used. Statistical analyses included
descriptive statistics, Pearson chi-square test and a multiple regression
model. Results. Among all participants, 43.9% reported fair or poor health.
Mean value of unhealthy days during the past 30 days was 10.4 days,
physically unhealthy days 6.4 days, mentally unhealthy days 5.3 days and
activity limitation days 4.3 days. Furthermore, 24.8% participants reported
having ≥14 unhealthy days, 14.9% had ≥14 physically unhealthy days, 11.8%
reported ≥14 mentally unhealthy days, and 9.4% had ≥14 activity limitation
days. Conclusion. This study addressed complex relationships between reflux
symptoms and patients’ impaired everyday lives.
Keywords: gastroesophageal reflux disease, burden, health-related quality of life