Srpski arhiv za celokupno lekarstvo 2015 Volume 143, Issue 9-10, Pages: 599-603
https://doi.org/10.2298/SARH1510599J
Full text ( 316 KB)
Auricular acantholytic squamous cell carcinoma with neck metastasis and lethal outcome: Case report
Jotić Ana (School of Medicine, Belgrade + Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade)
Ješić Snežana (School of Medicine, Belgrade + Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade)
Milovanović Jovica (School of Medicine, Belgrade + Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade)
Krstić Biljana (Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade)
Introduction. Acantholytic squamous cell (adenosquamous) carcinoma of the
skin are relatively rare subtype of squamous cell carcinoma, usually found in
elderly on sun-exposed areas of the skin, predominately head, neck and upper
extremities. Incidence of metastasis is 2-14%. Case Outline. A case of a
76-year-old male, with the signs of left-sided facial palsy and cervical mass
on the same side, is presented. Five months prior to the visit, due to
acantholytic squamous cell carcinoma, an excision of the ulceration of the
superior third of the left auricle was performed. Patient underwent surgical
treatment, after pathohistological and radiological confirmation of the
infiltrative neck metastasis. Postoperatively, rapid locoregional progression
of the disease was noted in the patient, with a lethal outcome. Conclusion.
Squamous cell carcinoma (including acantholytic subtype) with lesions bigger
than 4 cm in size in auricular-temporal region, signs of deep tissue
invasion, and lymphovascular and perineural invasion have higher local
metastatic potential. More frequent oncological check-ups with radiological
examination are necessary in detecting locoregional metastasis.
Keywords: acantholytic squamous cell carcinoma, local metastasis, lethal outcome