Srpski arhiv za celokupno lekarstvo 2015 Volume 143, Issue 7-8, Pages: 458-463
https://doi.org/10.2298/SARH1508458T
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Inflammatory myofibroblastic tumours of the respiratory tract: A series of three cases with varying clinical presentations and treatment
Tegeltija Dragana (Center for Pathology, Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica + Faculty of Medicine, Novi Sad)
Lovrenski Aleksandra 
(Center for Pathology, Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica + Faculty of Medicine, Novi Sad)
Stojanović Goran (Center for Bronchologic Diagnostics, Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica)
Bijelović Milorad (Faculty of Medicine, Novi Sad + Institute for Pulmonary Diseases of Vojvodina, Department for Thoracic Trauma, Sremska Kamenica)
Jeličić Ivana (General Hospital, Department for Pathology, Vrbas)
Eri Živka (Center for Pathology, Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica + Faculty of Medicine, Novi Sad)
Introduction. Inflammatory myofibroblastic tumor in the respiratory system is
a rare and controversial disease. It is macroscopically well-circumscribed,
non-encapsulated, firm and usually a yellowish-white mass. Histologically it
is composed of the following spindled and inflammatory cells: lymphocytes,
plasma cells, and histiocytes, including Touton type multinucleated giant
cells. Case Outline. The series included a 49-year-old man with a tracheal
inflammatory myofibroblastic tumor who complained of hoarseness; a
42-year-old man who was coughing and had a blood-stained sputum, and
inflammatory myofibroblastic tumor was in the right main and intermediate
bronchus; and a 32-yearold man with chest pain and inflammatory
myofibroblastic tumor as a solitary peripheral nodule in the left lower lobe.
In all the cases, the tumor was resected bronchoscopically and surgically.
Conclusion. Inflammatory myofibroblastic tumor of the lung and the trachea is
rare. Complete resection, when possible, should be the choice of treatment.
After the complete removal, prognosis is generally excellent and recurrences
are rare.
Keywords: inflammatory myofibroblastic tumor, lung, trachea