doiSerbia

Cost-effectiveness analysis of different types of labor for singleton pregnancy: Real life data

Lakić Dragana (Faculty of Pharmacy, Department of Social Pharmacy and Pharmacy Legislation, Belgrade)
Petrović Branko (Hospital for Gynecology and Obstetrics “Narodni Front”, Belgrade)
Petrova Guenka (Medical University, Faculty of Pharmacy, Department for Social Pharmacy, Sofia, Bulgaria)

Introduction. Views on the conduct of labor have changed over time, and a significant difference exists in relation to obstetric centers. Objective. To assess cost, clinical outcomes and cost-effectiveness of different types of labor in singleton pregnancies. Methods. A decision model was used to compare vaginal labor, induced labor and planned cesarean section. All data were taken from the Book of Labor from the University Hospital for Gynecology and Obstetrics “Narodni Front”, Belgrade, Serbia for labors conducted during one month period in 2011. Successful delivery (i.e. labor that began up to 42 gestation weeks, without maternal mortality and the newborn Apgar scores greater than or equal to seven in the fifth minute of life) was considered as the outcome of the cost effectiveness-analysis. To test the robustness of this definition probabilistic sensitivity analysis was performed. Results. From a total of 667 births, vaginal labor was conducted in 98 cases, induced vaginal in 442, while planned cesarean section was performed 127 times. Emergency cesarean section as a complication was much higher in the vaginal labor cohort compared to the induced vaginal cohort (OR=17.374; 95% CI: 8.522 to 35.418; p<0.001). The least costly type of labor was induced vaginal labor: average cost 461 euro, with an effectiveness of 98.17%. Both, vaginal and planned cesarean labor were dominated by the induced labor. The results were robust. Conclusion. Elective induction of labor was associated with the lowest cost compared to other types of labor, with favorable maternal and neonatal outcomes.

Keywords: cost-effectiveness, induction, labor

Projekat Ministarstva nauke Republike Srbije, br. 175035