Srpski arhiv za celokupno lekarstvo 2014 Volume 142, Issue 9-10, Pages: 586-588
https://doi.org/10.2298/SARH1410586Z
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Convexity meningioma associated with depression: A case report
Živković Nenad (Clinical Hospital Center Zemun, Department of Neurosurgery, Belgrade)
Marković Marko (Clinical Hospital Center Zemun, Department of Neurosurgery, Belgrade)
Spaić Milan (Clinical Hospital Center Zemun, Department of Neurosurgery, Belgrade)
Introduction. Meningiomas are slow growing, extra-axial lesions, and can be
neurologically silent for a long time and present only with depression. Case
Outline. A 65-year-old woman developed major depression and was treated with
antidepressants for two years. Depression failed to respond to drug treatment
and there was no improvement. Two months before admission to hospital, due to
the onset of epilepsy attack the patient underwent reinvestigation, and a
large temporal convexity meningioma, which corresponded in position to the
original electroencephalography focus, was diagnosed using the computer
topography of the brain. The patient underwent osteoplastic craniotomy, and a
left fronto-temporal convexity meningioma of 5 cm in diameter was completely
removed with its attachment to the dura. Histological examination confirmed a
fibroblastic meningioma. Conclusion. Total resection of convexity meningioma
and decompression of the brain tissue in the region of limbic pathways that
are involved, may contribute to a complete remission of depression symptoms.
This case also illustrates the need for a prompt neuroimaging of the brain
when patients present any atypical psychiatric symptoms, with late onset (>50
years old) of the first depressive episode or fast changes of the mental
state.
Keywords: meningioma, depression, surgical treatment