doiSerbia

Balloon valvuloplasty as a treatment of congenital aortic stenosis in children and adolescents

Parezanović Vojislav (Faculty of Medicine, Belgrade + University Children’s Hospital, Belgrade)
Đukić Milan (Faculty of Medicine, Belgrade + University Children’s Hospital, Belgrade)
Daehnert Ingo (Herzzentrum, Leipzig, Germany)
Gligić Ana (University Children’s Hospital, Belgrade)
Stefanović Igor (University Children’s Hospital, Belgrade)
Jovanović Ida (Faculty of Medicine, Belgrade + University Children’s Hospital, Belgrade)
Ilisić Tamara (University Children’s Hospital, Belgrade)
Ilić Slobodan (Faculty of Medicine, Belgrade + University Children’s Hospital, Belgrade)
Vulićević Irena (University Children’s Hospital, Belgrade)
Kalanj Jasna (University Children’s Hospital, Belgrade)

Introduction. Balloon valvuloplasty (BVP) is one of the primary therapies for congenital aortic stenosis in children and adolescents. The aim of this interventional procedure is to gain time before possible surgical therapy (aortic valve replacement) until adulthood. Objective. The aim of this study was to evaluate the efficacy, safety and mid-term results of transcatheter BVP in children and adolescent in our Center. Methods. From 2004 to 2011, 50 patients, aged 18 days to 18 years (mean 6.3 years) underwent BVP. Retrospective analysis of the echocardiographic and hemodynamic parameters were performed before and after procedure, especially peak pressure gradient (PG) across the aortic valve, semiquantification of the aortic regurgitation (AR) after the BVP as well as the left ventricle dimensions and functions. Results. The mean peak PG in the whole group decreased from 74.80±27.72 mm Hg to 27.86±13.04 mm Hg (p<0.001) after BVP. In 39 patients (78%), residual PG was lower than 30 mm Hg just after dilation. At the end of follow-up period, 25 patients (50%) had PG above 50 mm Hg, measured by Doppler technique, and four of them underwent re-dilation. Eight patients (16%) had severe AR. During the follow-up period (12-80 months, mean 51 months), six patients (12%) were referred to cardiac surgeons for aortic valve replacement or Ross procedure. Conclusions. This retrospective study analyzes our first experience of BVP as primary therapy of the congenital aortic stenosis. The results confirmed that BVP effectively postponed the need for surgery in children and adolescents toward the adulthood.

Keywords: congenital aortic stenosis, balloon valvuloplasty, children