Srpski arhiv za celokupno lekarstvo 2013 Volume 141, Issue 11-12, Pages: 758-763
https://doi.org/10.2298/SARH1312758M
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Sex differences of cardiovascular risk factors in patients with symptomatic carotid disease
Maksimović Miloš (Medicinski fakultet, Institut za higijenu i medicinsku ekologiju, Beograd)
Vlajinac Hristina (Medicinski fakultet, Institut za epidemiologiju, Beograd)
Radak Đorđe (Institut za kardiovaskularne bolesti „Dedinje“, Odsek za vaskularnu hirurgiju, Beograd + Medicinski fakultet, Beograd)
Marinković Jelena (Medicinski fakultet, Institut za medicinsku statistiku i informatiku, Beograd)
Maksimović Jadranka (Medicinski fakultet, Institut za epidemiologiju, Beograd)
Jorga Jagoda (Medicinski fakultet, Institut za higijenu i medicinsku ekologiju, Beograd)
Introduction. Cardiovascular diseases, especially heart disease and stroke
are the cause of more than a half of the total number of deaths in Serbia.
Objectives. The aim of the present study was to determine sex differences of
atherosclerotic risk factors in patients with symptomatic carotid disease.
Methods. The cross-sectional study, involving 657 consecutive patients with
verified carotid atherosclerotic disease, was performed in Belgrade, Serbia.
Sex differences of anthropometric parameters and atherosclerotic risk factors
were analyzed by means of the univariate logistic regression. Results. In
comparison with men, lower education and physical inactivity were
significantly more frequent in women, and the frequency of metabolic syndrome
(MetS), lower high-density cholesterol, abdominal obesity, body mass index
≥30.0 kg/m2, hypercholesterolemia and depression were also significantly
higher in women. Smoking and high serum uric acid level were significantly
more frequent in men than in women. Women had significantly higher number of
MetS components per person, but there were no significant sex differences in
the number of other risk factors. Out of all observed risk factors, including
MetS components, physical inactivity and hypertension were most frequent in
both sexes followed by ever smoking and low education in men and low
education and dyslipidemia in women. Conclusion. There were significant sex
differences in the distribution of some atherosclerotic risk factors, but not
in their number per person. Only the number of MetS components was
significantly higher in women.
Keywords: carotid disease, atherosclerotic risk factors, gender
Projekat Ministarstva nauke Republike Srbije,
br. III41002