Srpski arhiv za celokupno lekarstvo 2013 Volume 141, Issue 7-8, Pages: 460-465
https://doi.org/10.2298/SARH1308460M
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Relationship between abdominal obesity and other cardiovascular risk factors: cross sectional study of patients with symptomatic carotid disease
Maksimović Miloš (Medicinski fakultet, Institut za higijenu i medicinsku ekologiju, Beograd)
Vlajinac Hristina (Medicinski fakultet, Institut za epidemiologiju, Beograd)
Radak Đorđe (Institut za kardiovaskularne bolesti „Dedinje“, Beograd + Medicinski fakultet, Beograd)
Marinković Jelena (Medicinski fakultet, Institut za medicinsku statistiku i informatiku, Beograd)
Maksimović Jadranka (Medicinski fakultet, Institut za epidemiologiju, Beograd)
Jorga Jagoda (Medicinski fakultet, Institut za higijenu i medicinsku ekologiju, Beograd)
Introduction. Obesity, particularly visceral obesity, is considered one of
major risk factors for cardiovascular events. Objectives. The aim of the
present study was to investigate relationship between abdominal obesity and
other cardiovascular risk factors. Methods. The cross-sectional study
involved 657 consecutive patients with verified carotid atherosclerosis.
Carotid atherosclerosis was estimated by high resolution B-mode
ultrasonography. Abdominal obesity was defined as waist circumference >102 cm
in men and >88 cm in women. Results. Abdominal obesity was present in 324
(49.3%) participants. Multivariate analyses showed that abdominal obesity was
significantly positively associated with female sex, increased Baecke ’s Work
Index of physical activity at work, years of school completed <12, metabolic
syndrome, increased triglycerides, hyperglycemia and high serum uric acid.
Smoking, alcohol consumption, physical inactivity, hypertension, increased
total cholesterol, increased HDL and LDL cholesterols, increased high
sensitive C-reactive protein, increased fibrinogen, anti-lipid therapy and
anti-diabetic therapy were not significantly related to abdominal obesity.
Conclusion. Abdominal obesity among patients with symptomatic carotid disease
is significantly related to other cardiovascular risk factors, especially
metabolic syndrome, metabolic syndrome components and high level of serum
uric acid.
Keywords: abdominal obesity, carotid disease, risk factors
Projekat Ministarstva nauke Republike Srbije, br. III41002