Srpski arhiv za celokupno lekarstvo 2012 Volume 140, Issue 3-4, Pages: 142-147
https://doi.org/10.2298/SARH1204142H
Full text ( 253 KB)
Influence of initial visual field sensitivity on visual field loss progression in open angle glaucoma
Hentova-Senćanić Paraskeva (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Božić Marija (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Senćanić Ivan (Medicinski fakultet, Beograd + Klinika za očne bolesti, Kliničko-bolnički centar „Zvezdara”, Beograd)
Jovanović Miloš (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Stanković Branislav (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Marjanović Ivan (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Marković Vujica (Medicinski fakultet, Beograd + Klinika za očne bolesti, Klinički centar Srbije, Beograd)
Bjelović Nevena (Centar za vid „Oftalmika”, Beograd)
Introduction. It is important to know the risk factors for visual field
defect progression in order to predict the future development of glaucoma.
Objective. To investigate the influence of visual field initial sensitivity
on the rate of visual field progression. Methods. A minimum of five visual
fields were performed using computerized perimetry (Octopus) over a mean
follow- up 4-year period (48.85±17.84 months) in 64 persons (114 eyes) with
primary open angle glaucoma. The rate of change of the whole central visual
field and each of the seven regions of the field were measured by linear
regression analysis of the mean sensitivity value versus time. Based on the
slope of the regression line of visual field mean sensitivity over time the
eyes were divided into two groups: the group with stable and the group with
progressive visual field. The comparison of the mean sensitivity of the whole
central visual field between the groups was performed using the Mann-Whitney
U-test. The Spearman rang correlation coefficient and the Spearman
probability p values were calculated to assess the mean sensitivity of the
whole central visual field and of each visual field regions determined at the
beginning of the study. Results. The initial mean sensitivity of the whole
central visual field was lower in the group with progressive visual field
(16.62±6.35 dB). Correlation between the initial mean sensitivity and the
slope of the regression line was negative. The lowest mean sensitivity was in
the group with progressive visual field in the upper temporal (13.73±7.35
dB), nasal (14.74±7.23 dB) and upper nasal (15.03±7.75 dB) regions.
Conclusion. The lower mean sensitivity value of the visual field, especially
in the nasal and upper nasal visual field regions, carries a greater risk for
delayed progressive loss of the visual field in persons with glaucoma.
Keywords: glaucoma, computerized visual field, progression