Srpski arhiv za celokupno lekarstvo 2011 Volume 139, Issue 9-10, Pages: 657-660
https://doi.org/10.2298/SARH1110657S
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Syringomyelia in demyelinating disease of the central nervous system: Report of two cases
Savić Dejan (Klinika za neurologiju, Klinički centar, Niš)
Vojinović Slobodan (Klinika za neurologiju, Klinički centar, Niš)
Spasić Mirjana (Klinika za neurologiju, Klinički centar, Niš)
Perić Zoran (Klinika za neurologiju, Klinički centar, Niš)
Lukić Stevo (Klinika za neurologiju, Klinički centar, Niš)
Introduction. Syringomyelia is a cavitary extension inside the spinal cord
which can be either symptomatic or congenitally-idiopathic. Syringomyelia
during the course of the disease in patients presenting with clinically
definite multiple sclerosis was described earlier. Syringomyelia in patients
presenting with a clinically isolated syndrome suggestive of multiple
sclerosis is unusual. Case Outline. We present two patients presenting with
demy-elinating disease of the central nervous system with syringomyelia in
the cervical and thoracic spinal cord. We did not find classical clinical
signs of syringomyelia in our patients, but we disclosed syringomyelia
incidentally during magnetic resonance exploration. Magnetic resonance
exploration using the gadolinium contrast revealed the signs of active
demyelinating lesions in the spinal cord in one patient but not in the other.
Conclusion. Syringomyelia in demyelinating disease of the central nervous
system opens the question whether it is a coincidental finding or a part of
clinical features of the disease. Differentiation of the significance of
syringomyelia finding in these patients plays a role in the choice of
treatment concept in such patients.
Keywords: syringomyelia, demyelinating disease of the central nervous system, multiple sclerosis, clinically isolated syndrome
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