Srpski arhiv za celokupno lekarstvo 2011 Volume 139, Issue 7-8, Pages: 523-526
https://doi.org/10.2298/SARH1108523C
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Primary Burkitt’s lymphoma of the stomach
Čolović Nataša (Klinika za hematologiju, Klinički centar Srbije, Beograd + Medicinski fakultet, Beograd)
Radovanović Nebojša (Medicinski fakultet, Univerzitet u Beogradu, Beograd + Klinika za digestivnu hirurgiju, Klinički centar Srbije, Beograd)
Vidović Ana (Klinika za hematologiju, Klinički centar Srbije, Beograd + Medicinski fakultet, Beograd)
Čolović Milica (Klinika za hematologiju, Klinički centar Srbije, Beograd + Medicinski fakultet, Beograd)
Introduction. Burkitt’s lymphoma belongs to the group of non-Hodgkin’s
lymphomas with B immunophenotypic features of lymphoma cells. It has tendency
for extranodal localization primarily in the gastrointestinal tract and
retroperitoneum. Primary Burkitt’s lymphoma of the stomach is very rare.
Stomach is most frequently involved secondarily, growing from intrabdominal
tumorous mass into the stomach. Case Outline. The authors present a
30-year-old male in whom after 6 months duration of temporarily melaenas the
diagnosis of Burkitt’s lymphoma was established by endoscopic examination and
biopsy of ulceroinfiltrative lesion on the antral part of the stomach. The
patient was in clinical stage IIE. After one cycle of chemotherapy according
to protocol R-HyperCVAD, a subtotal distal gastrectomy and additional three
cycles of the same chemotherapeutic protocol a complete remission was
achieved. Conclusion. Burkitt’s lymphoma is a highly aggressive non-Hodgkin’s
lymphoma often present in extranodal sites. It should be treated with
systemic intensive chemotherapy and surgical removal of tumorous mass when
possible. Long-term survival using the combination therapy is possible to
achieve in 40-80% of patients.
Keywords: Burkitt’s lymphoma, polychemiotherapy, partial gastrectomy
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