Srpski arhiv za celokupno lekarstvo 2011 Volume 139, Issue 5-6, Pages: 376-379
https://doi.org/10.2298/SARH1106376S
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The importance of echocardiography in diagnostics of idiopathic pulmonary arterial hypertension: A case report
Stojković Gabrijela (Opšta bolnica, Leskovac)
Mladenov Sunčica (Opšta bolnica, Leskovac)
Jovanović Dimitrije (Opšta bolnica, Leskovac)
Stanković Aleksandar (Opšta bolnica, Leskovac)
Deljanin-Ilić Marina (Institut za prevenciju, lečenje i rehabilitaciju reumatskih i kardiovaskularnih bolesti „Niška Banja”, Niška Banja)
Ristić Arsen (Klinika za kardiovaskularne bolesti, Klinički centar Srbije, Beograd)
Introduction. Idiopathic pulmonary arterial hypertension (IPAH) is rare and
difficult progressive disease with prevalence of approximately 15 cases per
million residents, with predominant female cases. Case Outline. A 47-year-old
female presented with symptoms and signs of the right heart chambers failure.
Over prior seven years the patient had the feeling of suffocation and fatigue
when walking, and received treatment for bronchial asthma. Physical
examination revealed a marked loud second heart sound over the pulmonary
artery. Electrocardiogram: right ventricular hypertrophy. Spirometric
(pulmonary capacity) test, cardiac perfusion scan and spiral CT scanning
excluded secondary pulmonary arterial hypertension. Blood testing for
connective tissue diseases and HIV were within normal reference limits.
Transthoracic colour Doppler echocardiography demonstrated a mild tricuspid
regurgitation with high values of estimated maximal and middle systolic
pressure of the right ventricle (135/110 mm Hg), and excluded previous heart
disease. Cardiac catheterization confirmed IPAH diagnosis, with systolic
right ventricular pressure of 101/47/66 mm Hg and pulmonary capillary
pressure of 30/13/10 mm Hg. Basic therapy with sildenafil, nevertheless,
considerable limitations of strain tolerance was still present. Conclusion.
IPAH is a severe heart disease with non-specific signs and symptoms.
Screening for IPAH is transthoracic colour Doppler echocardiography shows
high correlation with cardiac catheterization.
Keywords: idiopathic pulmonary hypertension, aetiology, diagnosis, therapy
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