Srpski arhiv za celokupno lekarstvo 2011 Volume 139, Issue 5-6, Pages: 282-285
https://doi.org/10.2298/SARH1106282J
Full text ( 173 KB)
Cited by
Epidemic keratoconjunctivitis
Janićijević-Petrović Mirjana A. (Klinika za oftalmologiju, Klinički centar, Kragujevac)
Srećković Sunčica (Klinika za oftalmologiju, Klinički centar, Kragujevac)
Petrović Nenad (Klinika za oftalmologiju, Klinički centar, Kragujevac)
Šarenac Tatjana (Klinika za oftalmologiju, Klinički centar, Kragujevac)
Introduction. Keratocnjunctivitis is corneal and conjunctival inflammation
Clinical signs involve the irritating trio: mixed hyperemia of conjunctival
membranes, corneal subepthelial infiltrates and regional lymphadenopathy. The
most common causes of epidemic are adenovirus, herpes virus, and rarely
cytomegalovirus, which are now occurring with higher frequency as secondary
infections. Objective. The aim of the study was to present and analyze
keratoconjunctival epidemics in the region of Kragujevac from September 2008
to February 2009, as well as to analyze clinical features related to
virusological findings and etiology. Methods. In 329 patients we performed
clinical examination (biomicroscopy, fluorescent test, corneal sensitivity
test), collecting standard specimen of the conjuctiva and cornea, made
serological examination, and sent the specimens to the Virusology Institute
“Torlak” in Belgrade for the confirmation of epidemic etiology. The patients
were treated with local and symptomatological therapy. The epidemic was
eradicated in cooperation with a regional referent institution. All
outpatients activities were ceased, while hospital hygienic, sanitary,
intra-, extra-hospital and therapeutic procedures were undertaken. Results.
The distribution of 329 patients by gender was equivalent. Most patients were
aged from 27 to 34 years (25 %) of working population. The distribution of
patients by clinical features showed the predominance of follicular
hyperplasy (93.62%). The distribution according to the time of the first
symptoms onset showed the frequency of 50% of corneal infiltrate in the
second week. The period elapsed from the diagnosis to cure was three weeks in
50% of patients. Serological tests confirmed the mixed distribution of the
cause. Conclusion. Based on the authors’ experience, in order to eradicate
epidemics as fast as possible and achieve efficient treatment, it is
recommended that the epidemic should be reported, guidelines of referent
institutions be obeyed, all of which diminishes the recognizable professional
risk and decreases mistakes.
Keywords: epidemic keratoconjunctivitis, adenovirus, diagnosis, therapy
More data about this article available through SCIndeks