Srpski arhiv za celokupno lekarstvo 2011 Volume 139, Issue 3-4, Pages: 256-261
https://doi.org/10.2298/SARH1104256B
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Chronic fatigue syndrome
Brkić Snežana (Klinika za infektivne bolesti, Klinički centar Vojvodine, Novi Sad)
Tomić Slavica (Klinika za infektivne bolesti, Klinički centar Vojvodine, Novi Sad)
Ružić Maja (Klinika za infektivne bolesti, Klinički centar Vojvodine, Novi Sad)
Marić Daniela (Klinika za infektivne bolesti, Klinički centar Vojvodine, Novi Sad)
Chronic fatigue syndrome (CFS) is defined by a profound, debilitating
fatigue, lasting for at least 6 months and resulting in a substantial
reduction of occupational, personal, social and educational status. CFS is a
relatively poorly recognized clinical entity, although everyday experience
shows that there are many patients with CFS symptoms. The incidence and
prevalence of CFS remain unknown in most countries; however, the working
population is most affected with predominantly female patients in generative
period. Although, CFS was first mentioned four centuries ago, mysterious
aethiopathogensis of CFS still intrigues scientists as hundreds of studies
are still published every year on the subject. About 80 different
aetiological CFS factors are mentioned, which can be classified into five
basic groups: genetics, immunology, infectious diseases, endocrinology and
neuropsychiatry-psychology. Even today the condition is passed established
based on the diagnosis by exclusion of organic and psychiatric disorders,
which demands u multidisciplinary approach. As the syndrome is often
misdiagnosed and mistreated, self-medication is not uncommon in CFS
patients’. In addition, such patients usually suffer for years tolerating
severe fatigue. Thus, at the moment there are three priorities regarding CFS;
understanding pathogenesis, development of diagnostic tests and creating
efficient treatment program.
Keywords: chronic fatigue syndrome, aetiology, diagnosis
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