doiSerbia

Cholangiocellular carcinoma of the common hepatic duct causing obstructive jaundice in a patient with metastatic colonic carcinoma within liver

Čolović Radoje (Institut za bolesti digestivnog sistema, Klinički centar Srbije, Beograd)
Grubor Nikica (Institut za bolesti digestivnog sistema, Klinički centar Srbije, Beograd)
Radak Vladimir (Institut za bolesti digestivnog sistema, Klinički centar Srbije, Beograd)
Micev Marjan (Institut za bolesti digestivnog sistema, Klinički centar Srbije, Beograd)
Latinčić Stojan (Institut za bolesti digestivnog sistema, Klinički centar Srbije, Beograd)

Introduction. Colorectal carcinoma, one of the most frequent carcinomas, produces liver metastasis very frequently. Surprisingly, those secondaries rarely cause obstructive jaundice. If it appears, it is usually caused by compression or infiltration of the major bile ducts close to the hepatic hilus, less frequently with bile duct obstruction by gelatinous mucus produced by the tumour, much rarer by the tumour growth within the, otherwise intact, common bile duct and very rarely by metastasis into the biliary tree. Case Outline. We present a 67-year-old man who had been submitted to left colectomy for sygmoid colon carcinoma four years earlier, now, admitted with an obstructive jaundice, along with a number of liver and lung secondaries. Obstructive jaundice was caused by the vegetative tumour of the proximal part of the common hepatic duct which was resected and anastomosed with a Roux-en-Y jejunal limb. The postoperative recovery was uneventful. The patient died 7 months later without jaundice due to liver and lung secondaries. Histological findings showed cholangiocellular carcinoma of the common hepatic duct, while the histological findings of the liver tumour specimen confirmed metastatic colonic carcinoma. Conclusion. In case of obstructive jaundice in patients with metastatic colonic carcinoma within liver, other aethiological factors of biliary obstruction can not be excluded and have to be taken into differential diagnosis.

Keywords: colorectal carcinoma, metastases within liver, cholangiocellular carcinoma, obstructive jaundice