doiSerbia

Laparoscopic ovary biopsy and infertility

Popović Jasmina (Ginekološko-akušerska klinika, Medicinski fakultet, Niš)
Šulović Vojin (Srpska akademija nauka i umetnosti, Beograd)
Vučetić Dragomir (Ginekološko-akušerska klinika, Medicinski fakultet, Niš)
Pop-Trajković Zoran (Ginekološko-akušerska klinika, Medicinski fakultet, Niš)
Veljković Milena (Dom zdravlja, Niš)

In the most developed countries, laparoscopic diagnostics and surgical procedures in the chosen cases still play a very important role and represent the acceptable alternative to the extrauterine fertilization. On the basis of histopathological verification of ovary biopsy cuts taken during the laparoscopy, the optimum conditions are fulfilled for determination of the ovary potentiality enabling the selection of patients for the further proper treatment. 113 patients that, due to the marriage infertility, were examined and treated at the Department of Sterility and Infertility of the Obstetrics and Gynecology Clinic, Clinical Center of Niš with the average age of 31.39 ± 6.10 and with the average marriage infertility period lasting from 4.11±2.99 had undergone the surgical laparoscopy. The most frequently used interventions that were performed disregarding the adnexial findings, were salipongovariolyses in 73 cases (64.60%), then fimbrioplastic in 60 cases (53.10%). Ovary biopsy and histopathological analysis of the cuts taken were performed in 110 patients (89.39%). We got 105 histopathological findings. The most common histopathological findings showed the existence of the primordial folicules in 39.60% of women, with the prevalence in younger ones. (In patients younger than 20 - 66.67%, while in patients over 40 - 25%). We found out that the prevailing number of women had the histological findings that spoke on behalf of the potential ovaries in case the infertility lasted shorter. The ovary tissue cuts taken by biopsy that were histopathologically analyzed showed the significantly higher pregnancy and delivery rate in findings with the primordial folicules present (67.5% of the pregnancy rate 57.5% of the intrauterine pregnancy rate and 47.5% of the delivery rate).

Keywords: infertility, laparoscopy, ovary biopsy, histopathologicall analysis, pregnancy rate