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Srpski arhiv za celokupno lekarstvo 2002 Volume 130, Issue 3-4, Pages: 73-80
https://doi.org/10.2298/SARH0204073J
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Slowing down of chronic renal failure progression with captopril in spontaneously hypertensive rats with adriamycin nephropathy

Jovanović Dijana B. (Nefrološka Klinika Kliničkog centra Srbije, Beograd)
Jovović Đurđica (Institut za medicinska istraživanja, Beograd)
Varagić Jasmina (Institut za medicinska istraživanja, Beograd)
Dimitrijević Jovan (Nefrološka Klinika Kliničkog centra Srbije, Beograd)
Dragojlović Zorica (Medicinska biohemija Kliničkog centra Srbije, Beograd)
Đukanović Ljubica D. (Nefrološka Klinika Kliničkog centra Srbije, Beograd)

In SHRs with ADR nephropathy treatment with captopril normalized systemic blood pressure, and slowed down CRF progression in their early stage. These functional changes correlate with significant slowing of glomerular and interstitial changes.

Keywords: Renal failure, chronical, captopril, adriamycin nephropathy

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