doiSerbia

Diffusion disorder in liver cirrhosis

Ćulafić Đorđe (Institut za digestivne bolesti Kliničkog centra Srbije, Beograd)
Perišić Mirjana D. (Institut za digestivne bolesti Kliničkog centra Srbije, Beograd)
Rebić Predrag M. (Institut za plućne bolesti i tuberkulezu Kliničkog centra Srbije)

The impairment of diffusion capacity is a very common functional disorder in patients with liver cirrhosis and portal hypertension. Disproportionately higher reduction of the transfer factor compared to restrictive ventilatory disorder, suggests that diffusion disorder is primarily induced by inadequate pulmonary perfusion. The isolated reduction of the transfer factor cannot be only explained in each case by intrapuimonary vascular dilatation.

Keywords: Lung transfer factor, liver cirrhosis