Presently, the cyclotrons are playing a very important role in the production of radionuclides for medicine, which are very safe and reliable installations. From radioisotopes produced with cyclotrons, it is rather easy to select one that has appropriate nuclear-physical characteristics for medical use, in comparison to the ones produced with reactors. At PNPI, a high current cyclotron C-80 with the energy of extracted proton beam of 40-80 MeV and the current up to 200 μA is under construction. One of the main goals of C-80 is the production of a wide spectrum of medical radionuclides for diagnostics and therapy. At present time, a project is worked out for the construction of radioisotope complex RIC-80 (Radioisotopes at the cyclotron C-80) at the beam of C-80. In the presented submission, the project of RIC-80 complex is discussed, which includes three target stations for the production of a large set of radionuclides for medicine. The peculiarity of the proposed radioisotope facility is the use of the mass-separator with the target-ion source device as one of the target stations for on-line, or semi on-line production of a high purity separated radioisotopes. The first results on the target development for production of different medical radionuclides, including radioisotope generator for PET diagnostics ⁸²Sr, are presented as well.

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