Purpose
CNS tuberculosis is a leading cause of morbidity and mortality in developing countries, caused by Mycobacterium tuberculosis. There is further worsening of the scenario even in developed countries due to increasing numbers of HIV infected patients. Classical presentation of CNS tuberculosis poses no problem for clinicians. However, giant tuberculomas and solitary ring enhancing lesions present as diagnostic challenge because they simulate many infectious and non-infectious medical conditions. The purpose of our scientific exhibit is: Highlights the characteristic imaging features of CNS tuberculosisEmphasis on giant tuberculomas...
Methods and Materials
Material and methods This retrospective study includes 21 patients of either surgically or clinically (mainly response to ATT) proven CNS tuberculosis. These patients presented with varied clinical features such as fever, headache, nausea, vomiting, photophobia, cranial nerve palsies, limb weakness and altered sensorium with signs & symptoms localized to the topographic location of tuberculomas. There were 13 male and 8 female patients with age range between 9 to 70 years (Mean age- 30years). Imaging was performed either with MDCT, MRI or both. Routine pulse sequences...
Results
Purpose CNS tuberculosis is a leading cause of morbidity and mortality in developing countries, caused by Mycobacterium tuberculosis. There is further worsening of the scenario even in developed countries due to increasing numbers of HIV infected patients. Classical presentation of CNS tuberculosis poses no problem for clinicians. However, giant tuberculomas and solitary ring enhancing lesions present as diagnostic challenge because they simulate many infectious and non-infectious medical conditions. The purpose of our scientific exhibit is: Highlights the characteristic imaging features of CNS tuberculosisEmphasis on giant...
Conclusion
Classical imaging findings pose no problem for diagnosis of CNS tuberculosisCases of giant or solitary ring enhancing lesions keep on increasing which mimic other infectious and non-infectious pathologiesAtypical clinical signs and symptoms are not unusualHigh index of clinical suspicion is required for diagnosisProfound T2W hypointensity is reliable predictor for giant tuberculomas with intense contrast enhancement, especially in deep locations‘Outer rim excrescence’ sign may contribute in cases of ring and solid enhancing lesions, however it requires further comprehensive study to record as a differentiating feature
References
REFERENCE Jinkins JR, Gupta R, Chang KH, et al. MR imaging of central nervous system tuberculosis. Radiol Clin North Am 1995;33:771–86Gupta RK, Jena A, Sharma A, Guha DK, Khushu S, Gupta AK. MR imaging of intracranial tuberculoma. J Comput Assist Tomogr 1988;12:280–285Gupta RK, Pandey P, Khan EM, Mittal P, Gujral RB, Chhabra DK.Intracranial tuberculomas: MRI signal intensity correlation with histopathologyand localized proton spectroscopy. Magn Reson Imag1993;11:443–449Gupta RK, Kathuria MK, Pradhan S. Magnetization transfer MR imaging in CNS tuberculosis. AJNR Am J Neuroradiol 1999;20:867-75Gupta RK, Jena...
Personal Information
D.KUMAR*, R. Sheoran*-Department of Radiodagnosis and imagingS. K. Bansal*-Department of NeurosurgeryO. P. Arora*- Department of Neurology*ARORA NEURO CENTRE,LUDHIANA,PUNJAB,
[email protected]