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Cartilage and Osteoarthritis

  • Book
  • © 2004

Overview

Editors:
  1. Frédéric Ceuninck

    1. Division de Rhumatologie, Institut de Recherches Servier, Suresnes, France

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  2. Massimo Sabatini

    1. Division de Rhumatologie, Institut de Recherches Servier, Suresnes, France

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    You can also search for this editor in PubMed   Google Scholar

  3. Philippe Pastoureau

    1. Division de Rhumatologie, Institut de Recherches Servier, Suresnes, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 101)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Generation and Use of Transgenic Mice As Models of Osteoarthritis

    • Anna-Marja Säämänen, Eero Vuorio
    Pages 1-23

  3. Development and Clinical Application in Arthritis of a New Immunoassay for Serum Type IIA Procollagen NH2 Propeptide

    • Jean-Charles Rousseau, Linda J. Sandell, Pierre D. Delmas, Patrick Garnero
    Pages 25-37

  4. Histological and Immunohistological Studies on Cartilage

    • James Melrose, Susan Smith, Peter Ghosh
    Pages 39-63

  5. Histochemical Visualization of the Cartilage Hyaladherins Using a Biotinylated Hyaluronan Oligosaccharide Bioaffinity Probe

    • James Melrose, Susan Smith
    Pages 65-78

  6. Methods for Cartilage and Subchondral Bone Histomorphometry

    • Philippe Pastoureau, Agnès Chomel
    Pages 79-91

  7. Laser-Mediated Microdissection As a Tool for Molecular Analysis in Arthritis

    • Martin Judex, Elena Neumann, Steffan Gay, Ulf Müller-Ladner
    Pages 93-105

  8. Analysis of Protein Distribution in Cartilage Using Immunofluorescence and Laser Confocal Scanning Microscopy

    • Stephan Soeder, Alexander Kuhlmann, Thomas Aigner
    Pages 107-125

  9. Molecular and Biochemical Assays of Cartilage Components

    • Caroline D. Hoemann
    Pages 127-156

  10. Mechanical Characterization of Native and Tissue-Engineered Cartilage

    • Albert C. Chen, Stephen M. Klisch, Won C. Bae, Michele M. Temple, Kevin B. McGowan, Kenneth R. Gratz et al.
    Pages 157-190

  11. Noninvasive Study of Human Cartilage Structure by MRI

    • Felix Eckstein
    Pages 191-217

  12. High-Resolution MRI Techniques for Studies in Small-Animal Models

    • Olivier Beuf
    Pages 219-229

  13. High-Resolution Imaging of Osteoarthritis Using Microcomputed Tomography

    • Lydia Wachsmuth, Klaus Engelke
    Pages 231-248

  14. High-Resolution Ultrasonography for Analysis of Age- and Disease-Related Cartilage Changes

    • Amena Saïed, Pascal Laugier
    Pages 249-265

  15. Evaluation of Cartilage Composition and Degradation by High-Resolution Magic-Angle Spinning Nuclear Magnetic Resonance

    • Jürgen Schiller, Daniel Huster, Beate Fuchs, Lama Naji, Jörn Kaufmann, Klaus Arnold
    Pages 267-285

  16. Pulsed-Field Gradient-Nuclear Magnetic Resonance (PFG NMR) to Measure the Diffusion of Ions and Polymers in Cartilage

    • Jürgen Schiller, Lama Naji, Robert Trampel, Wilfred Ngwa, Robert Knauss, Klaus Arnold
    Pages 287-302

  17. Dynamics of Collagen in Articular Cartilage Studied by Solid-State NMR Methods

    • Daniel Huster, Jürgen Schiller, Klaus Arnold
    Pages 303-318

  18. Computerized Protocol for Anatomical and Functional Studies of Joints

    • Sandra Martelli, Stefano Zaffagnini
    Pages 319-338

  19. Back Matter

    Pages 339-343
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Keywords

About this book

An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for the study-at the tissue level-of turnover, structure, and functioning of normal and diseased articular cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists with readily reproducible protocols for new experiments to understand-from the cellular to the animal level-the pathophysiology of cartilage and to discover molecular targets for pharmacological intervention.

Reviews

"This is a high quality laboratory manual that provides detailed instructions for conducting experiments directed at studying the role of cartilage in osteoarthritis. Overall, this would be a worthwhile book to keep in the laboratory for anyone studying the molecular mechanisms of connective tissue diseases."-Doody's Health Sciences Book Review Journal

Editors and Affiliations

  • Division de Rhumatologie, Institut de Recherches Servier, Suresnes, France

    Frédéric Ceuninck, Massimo Sabatini, Philippe Pastoureau

Bibliographic Information

  • Book Title: Cartilage and Osteoarthritis

  • Editors: Frédéric Ceuninck, Massimo Sabatini, Philippe Pastoureau

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592598218

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2004

  • Hardcover ISBN: 978-1-58829-505-7Published: 04 August 2004

  • Softcover ISBN: 978-1-61737-606-1Published: 10 November 2010

  • eBook ISBN: 978-1-59259-821-2Published: 02 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XIV, 346

  • Topics: Orthopedics

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