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Clinical, Microbiological, and Economic Benefit of a Change in Antibiotic Prophylaxis for Cardiac Surgery

Published online by Cambridge University Press:  02 January 2015

Denis Spelman ,
Glenys Harrington ,
Phil Russo  and
S. Wesselingh
Denis Spelman*
Affiliation:
Infection Control and Hospital Epidemiology Unit, Alfred Hospital, Prahran, Victoria, Australia
Glenys Harrington
Affiliation:
Infection Control and Hospital Epidemiology Unit, Alfred Hospital, Prahran, Victoria, Australia
Phil Russo
Affiliation:
Infection Control and Hospital Epidemiology Unit, Alfred Hospital, Prahran, Victoria, Australia
S. Wesselingh
Affiliation:
Infection Control and Hospital Epidemiology Unit, Alfred Hospital, Prahran, Victoria, Australia
*
Microbiology, Alfred Hospital, Commercial Road, Prahran 3181, Australia
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Abstract

Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 23 , Issue 7 , July 2002 , pp. 402 - 404
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2002

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