Journal of Biological Chemistry
Molecular Bases of DiseaseSmall Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models*
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This work was supported by the NCATS Intramural Research Program, Molecular Libraries Initiative of the National Institutes of Health Common Fund, National Institutes of Health Grant U54 MH 084681, Alabama Drug Discovery Alliance, National Institutes of Health/NCI Grant 5P30CA13148-37, and Translational Research Grant from the Leukemia & Lymphoma Society Grant 6237-13. The authors declare that they have no conflicts of interest with the contents of this article. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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Both authors contributed equally to this work.
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Present address: Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, Cambridge, MA 02139.