Journal of Biological Chemistry
Volume 289, Issue 46, 14 November 2014, Pages 31983-31994
Membrane BiologyPlasma Membrane Cholesterol as a Regulator of Human and Rodent P2X7 Receptor Activation and Sensitization*
Under a Creative Commons license
open access
Cited by (0)
- *
This work was supported by the Biotechnology and Biological Sciences Research Council (BB/F001320/1) (to R. D. M. L.).
- 1
Funded by the David James Studentship, Department of Pharmacology, University of Cambridge.
- 2
Funded by a Marshall Scholarship.
- 4
The abbreviations used are:
- MCD
methyl-β-cyclodextrin
- αCD
α-cyclodextrin
- BrP
bromopalmitate
- NES
normal extracellular solution
- RD NES
reduced divalent normal extracellular solution
- NMDG+
N-methyl-d-glucamine
- TMD
transmembrane domain
- CRAC
cholesterol recognition amino acid consensus
- BzATP
3′-O-(4-benzoyl)-benzoyl adenosine 5′-triphosphate
- DMSO
dimethyl sulfoxide
- aa
amino acids
- z
benzyloxycarbonyl
- fmk
fluoromethylketone
- pF
picofarads.
© 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.