Issue 19, 2013

Recent advances in the Willgerodt–Kindler reaction

Abstract

The Willgerodt–Kindler reaction has, in recent years, received limited attention and application in synthetic organic chemistry. With the advent of new technology such as microwave-assisted heating, several new, high-yielding, practical, and more environmentally friendly reaction protocols have been developed. This review aims to once again draw attention to this relatively underutilised process by highlighting the recent developments in the Willgerodt–Kindler reaction in the synthesis of (thio)amides, carboxylic acids, and heterocycles.

Graphical abstract: Recent advances in the Willgerodt–Kindler reaction

Article information

Article type
Review Article
Submitted
10 May 2013
First published
24 Jun 2013

Chem. Soc. Rev., 2013,42, 7870-7880

Recent advances in the Willgerodt–Kindler reaction

D. L. Priebbenow and C. Bolm, Chem. Soc. Rev., 2013, 42, 7870 DOI: 10.1039/C3CS60154D

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