Issue 10, 2014

Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

Abstract

This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future.

Graphical abstract: Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

Article information

Article type
Minireview
Submitted
11 Jan 2014
Accepted
11 Feb 2014
First published
24 Mar 2014
This article is Open Access
Creative Commons BY license

Polym. Chem., 2014,5, 3291-3297

Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

A. Pitto-Barry and N. P. E. Barry, Polym. Chem., 2014, 5, 3291 DOI: 10.1039/C4PY00039K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements