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Undiagnosed hypertension in a rural district in Bangladesh: The Bangladesh Population-based Diabetes and Eye Study (BPDES)

Abstract

Hypertension is mainly asymptomatic and remains undiagnosed until the disease progresses. The objective of the study was to determine the prevalence of and risk factors for hypertension in rural Bangladesh. Using a population-based cluster random sampling strategy, 3096 adults aged 30 years were recruited from a rural district in Bangladesh. Data collected included two blood pressure (BP) measurements, fasting blood glucose, socio-demographic and anthropometric measurements. Hypertension was defined as systolic BP (SBP) 140 mm Hg or diastolic BP (DBP) 90 mm Hg or self-reported diagnosed hypertension. Logistic regression techniques were used for data analyses. The crude prevalence of hypertension was 40% (95% confidence interval (CI) 38–42%) of which 82% were previously undiagnosed. People from lower socio-economic status (SES) had a significantly higher percentage of undiagnosed hypertension compared with people with higher SES (P<0.001). There was no significant gender difference in severity of hypertension. Males with higher education level compared with no education had a higher prevalence of hypertension (odds ratio 2.34, 95% CI 1.49–3.69). Older age and waist circumference in both genders, and diabetes, lack of physical activity in females were found to be associated with higher prevalence of hypertension. Our research suggests the prevalence of undiagnosed hypertension was higher in the rural area in Bangladesh than that reported from the rural area in neighbouring India and China. Lower SES was associated with a higher risk of undiagnosed hypertension. Public health programs at the grass-roots level must emphasise the provision of primary care and preventive services in managing this non-communicable disease.

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References

  1. WHO. A global brief on hypertension. 2013.

  2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr et al. National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560–2572.

    Article  CAS  PubMed  Google Scholar 

  3. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J . Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365: 217–223.

    PubMed  Google Scholar 

  4. Wong TY, Mitchell P . Hypertensive retinopathy. N Engl J Med 2004; 351: 2310–2317.

    Article  CAS  PubMed  Google Scholar 

  5. Wong TY, Mitchell P . The eye in hypertension. Lancet 2007; 369: 425–435.

    Article  PubMed  Google Scholar 

  6. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R and Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903–1913.

    Article  PubMed  Google Scholar 

  7. Joshi SR, Saboo B, Vadivale M, Dani SI, Mithal A, Kaul U et al. SITE Investigators. Prevalence of diagnosed and undiagnosed diabetes and hypertension in India—results from the Screening India's Twin Epidemic (SITE) study. Diabetes Technol Ther 2012; 14: 8–15.

    Article  PubMed  Google Scholar 

  8. Li H, Meng Q, Sun X, Salter A, Briggs NE, Hiller JE . Prevalence, awareness, treatment, and control of hypertension in rural China: results from Shandong Province. Journal of hypertension 2010; 28: 432–438.

    Article  CAS  PubMed  Google Scholar 

  9. Krishnani A, Garg R, Kahandaliyanage A . Hypertension in the South-East Asia Region: an overview. Regional Health Forum 2013; 17: 7–14.

    Google Scholar 

  10. Bangladesh Demographic and Health Survey. National Institute of Population Research and Training, Dhaka, Bangladesh 2011.

  11. Parr JD, Lindeboom W, Khanam MA, Perez Koehlmoos TL . Diagnosis of chronic conditions with modifiable lifestyle risk factors in selected urban and rural areas of Bangladesh and sociodemographic variability therein. BMC Health Serv Res 2011; 11: 309.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Busingye D, Arabshahi S, Subasinghe AK, Evans RG, Riddell MA, Thrift AG . Do the socioeconomic and hypertension gradients in rural populations of low- and middle-income countries differ by geographical region? A systematic review and meta-analysis. Int J Epidemiol 2014; 43: 1563–1577.

    Article  PubMed  Google Scholar 

  13. Islam AK, Majumder AA . Hypertension in Bangladesh: a review. Indian Heart J 2012; 64: 319–323.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Sayeed MA, Mahtab H, Khanam PA, Begum R, Banu A, Azad Khan AK . Diabetes and hypertension in pregnancy in a rural community of Bangladesh: a population-based study. Diabet Med 2005; 22: 1267–1271.

    Article  CAS  PubMed  Google Scholar 

  15. Shrivastava SR, Shrivastava PS, Ramasamy J . The determinants and scope of public health interventions to tackle the global problem of hypertension. Int J Prev Med 2014; 5: 807–812.

    PubMed  PubMed Central  Google Scholar 

  16. Bhansali A, Dhandania VK, Deepa M, Anjana RM, Joshi SR, Joshi PP et al. Prevalence of and risk factors for hypertension in urban and rural India: the ICMR-INDIAB study. J Hum Hypertens 2014; 29: 204–209.

    Article  PubMed  Google Scholar 

  17. Alam DS, Chowdhury MA, Siddiquee AT, Ahmed S, Niessen LW . Awareness and control of hypertension in Bangladesh: follow-up of a hypertensive cohort. BMJ Open 2014; 4: e004983.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Basgram Union Parisad Office, Electoral list: Dariapur, Narail, Bangladesh 2011.

  19. Bangladesh Bureau of Statistics. Population and Housing Census 2010.

  20. IDF. International Diabetes Atlas Fifth edition http://www.idf.org/atlasmap/atlasmap2012.

  21. Chakrabarti R, Finger RP, Lamoureux E, Islam MT, Dirani M, Bhuiyan MA et al. Rationale and methodology for a population-based study of diabetes and common eye diseases in a rural area in Bangladesh: Bangladesh Population-based Diabetes and Eye Study (BPDES). Bangladesh Journal of Medical Science 2015 (in press).

  22. Islam FM, Chakrabarti R, Dirani M, Islam MT, Ormsby G, Wahab M et al. Knowledge, attitudes and practice of diabetes in rural Bangladesh: The Bangladesh Population Based Diabetes and Eye Study (BPDES). PLoS ONE 2014; 9: e110368.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Whitworth JA and World Health Organization ISoHWG. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 2003; 21: 1983–1992.

    Article  PubMed  Google Scholar 

  24. Cheng YH, Chi I, Boey KW, Ko LS, Chou KL . Self-rated economic condition and the health of elderly persons in Hong Kong. Soc Sci Med 2002; 55: 1415–1424.

    Article  CAS  PubMed  Google Scholar 

  25. Akter S, Rahman MM, Abe SK, Sultana P . Prevalence of diabetes and prediabetes and their risk factors among Bangladeshi adults: a nationwide survey. Bull World Health Organ 2014; 92: 204–213, 213A.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Zaman M, Taleb A, Rahman S, Acharyya A, Islami FA, Ahmed MSAM et al. Prevalence of hypertension among the Bangladeshi adult population: a meta-analysis. Regional Health Forum 2013; 17: 15–19.

    Google Scholar 

  27. Saquib N, Saquib J, Ahmed T, Khanam MA, Cullen MR . Cardiovascular diseases and type 2 diabetes in Bangladesh: a systematic review and meta-analysis of studies between 1995 and 2010. BMC Public Health 2012; 12: 434.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Devi P, Rao M, Sigamani A, Faruqui A, Jose M, Gupta R et al. Prevalence, risk factors and awareness of hypertension in India: a systematic review. J Hum Hypertens 2013; 27: 281–287.

    Article  CAS  PubMed  Google Scholar 

  29. Hypertension Study G. Prevalence, awareness, treatment and control of hypertension among the elderly in Bangladesh and India: a multicentre study. Bull World Health Organ 2001; 79: 490–500.

    Google Scholar 

  30. Klein R, Klein BE, Lee KE, Cruickshanks KJ, Moss SE . The incidence of hypertension in insulin-dependent diabetes. Arch Intern Med 1996; 156: 622–627.

    Article  CAS  PubMed  Google Scholar 

  31. Sowers JR, Epstein M, Frohlich ED . Diabetes, hypertension, and cardiovascular disease: an update. Hypertension 2001; 37: 1053–1059.

    Article  CAS  PubMed  Google Scholar 

  32. Arauz-Pacheco C, Parrott MA, Raskin P . The treatment of hypertension in adult patients with diabetes. Diabetes Care 2002; 25: 134–147.

    Article  PubMed  Google Scholar 

  33. Mohan V, Seedat YK, Pradeepa R . The rising burden of diabetes and hypertension in southeast asian and african regions: need for effective strategies for prevention and control in primary health care settings. Int J Hypertens 2013; 2013: 409083.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. BMJ 1998; 317: 703–713.

  35. Snow V, Weiss KB, Mottur-Pilson C and Clinical Efficacy Assessment Subcommittee of the American College of P. The evidence base for tight blood pressure control in the management of type 2 diabetes mellitus. Ann Intern Med 2003; 138: 587–592.

    Article  PubMed  Google Scholar 

  36. Yadav S, Boddula R, Genitta G, Bhatia V, Bansal B, Kongara S et al. Prevalence & risk factors of pre-hypertension & hypertension in an affluent north Indian population. Indian J Med Res 2008; 128: 712–720.

    CAS  PubMed  Google Scholar 

  37. Levenstein S, Smith MW, Kaplan GA . Psychosocial predictors of hypertension in men and women. Arch Intern Med 2001; 161: 1341–1346.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

We thank the BPDES study coordinator and the volunteers involved in data collection. We also thank Omron for donating the diabetes and hypertension measuring tools. The authors did not receive any financial support for this research.

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Correspondence to F M A Islam.

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Islam, F., Bhuiyan, A., Chakrabarti, R. et al. Undiagnosed hypertension in a rural district in Bangladesh: The Bangladesh Population-based Diabetes and Eye Study (BPDES). J Hum Hypertens 30, 252–259 (2016). https://doi.org/10.1038/jhh.2015.65

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