Trends in Cancer
ForumCancer Is Not (Only) a Senescence Problem
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Acknowledgments
This work was supported by the ANR (Blanc project EVOCAN), the CNRS (INEE), an International Associated Laboratory Project France/Australia, the Montpellier Hérault Sport Club M.H.S.C, and André Hoffmann (Fondation MAVA).
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Cited by (17)
Ability of animals to detect cancer odors
2023, Biochimica et Biophysica Acta - Reviews on CancerCitation Excerpt :For species with post-reproductive cancer, selection should not play a role on social interactions since the cancer will not affect the fitness of breeders. However, oncogenic processes may appear at a younger age in some species, or in the case of transmissible cancers, it is possible that selection plays a role in the olfactory capacities of animals to enable them to avoid conspecifics in poor conditions [100–102]. Oncogenic agents such as UV radiation, oncogenic contaminants, and hormones released into waterways are increasingly present in the environment due to human encroachment and habitat degradation.
Tumors alter life history traits in the freshwater cnidarian, Hydra oligactis
2022, iScienceCitation Excerpt :The failure to remove abnormally proliferating cells may lead to the formation of neoplasms, also called tumors, which can be detrimental to the fitness of their bearers being, for instance, lethal at the metastatic stage (Dillekås et al., 2019; Lloyd et al., 2017). Although neoplasm formation is usually a slow process and can theoretically occur at any age in organisms of most multicellular species (Thomas et al., 2018), the importance of neoplastic cells for animal evolutionary ecology is largely unknown (Boutry et al., 2022a; Thomas et al., 2017). The ecological and evolutionary importance of cancer is an increasingly timely topic given the accumulating levels of carcinogenic pollutants in ecosystems because of anthropic activities (Giraudeau et al., 2018).
The evolution and ecology of benign tumors
2022, Biochimica et Biophysica Acta - Reviews on CancerCitation Excerpt :However, conventional wisdom holds that most oncogenic manifestations occur in the post-reproductive period, because natural selection is weak during that stage. Even if this argument is questionable given that even cancer at subclinical levels may be important to consider [189], it does not apply to the majority of benign tumors. Benign tumors often occur earlier than malignant ones, particularly when the benign stage is a precursor of malignant lesions (e.g. as seen before, this is the case in adenoma-to-carcinoma, where successive benign stages occur earlier in life [190–192]).
The evolution of resistance and tolerance as cancer defences
2020, ParasitologyBehavioural ecology meets oncology: Quantifying the recovery of animal behaviour to a transient exposure to a cancer risk factor
2024, Proceedings of the Royal Society B: Biological Sciences