Forensic Population Genetics – Short Communication
Y-STR genetic diversity in autochthonous Andalusians from Huelva and Granada provinces (Spain)

https://doi.org/10.1016/j.fsigen.2011.05.007Get rights and content

Abstract

Seventeen Y-chromosomal short tandem repeats (STRs) were analyzed in 347 healthy, unrelated, autochthonous males from the Andalusian provinces of Huelva (N = 167) and Granada (N = 180). AmpFlSTR Y-filer PCR Amplification kit (Applied Biosystems) was used to type the Y-STR markers. A total of 156 and 166 different haplotypes for the 17 Y-STR set were detected in Huelva, and Granada, respectively. The same haplotype diversity was found for both samples (0.998 ± 0.001), and the overall discrimination capacity was 0.904. The most common minimal haplotype (DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393) in both subpopulations was 14-13-16-24-11-13-13, which is also the most frequent haplotype among Atlantic European populations. Comparison analysis using pairwise RST values and Analysis of Molecular Variance (AMOVA) revealed a significant genetic distance between our Andalusian samples and other ones from the northern Iberian fringe (including Basque and Pyrenean populations). However, results from the multi-dimensional scaling analysis (MDS) yielded a well-defined group of Iberian populations separated from the other Mediterranean clusters observed.

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Acknowledgements

We gratefully acknowledge all doctors, nurses and Andalusian donors who generously participated in this research. In addition, we are indebted to Dr. A. Fernández-Montoya and Dr. D. Prados, Directors of the Blood Transfusion Centres of Granada and Huelva, respectively, as well as to Dr. Antonio Fernández-Jurado, Head of the Haematology Service of the Juan Ramón Jiménez Hospital in Huelva. Financial support has been provided by the Spanish Ministry of Science and Innovation: Research Projects:

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