In FocusThe keto diet and the gut: cause for concern?
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Can dietary patterns prevent cognitive impairment and reduce Alzheimer's disease risk: Exploring the underlying mechanisms of effects
2022, Neuroscience and Biobehavioral ReviewsCitation Excerpt :Collectively, a KD or KBs could alleviate cognitive impairment in clinical trials. However, 30–50% of individuals who follow KD have side effects such as nausea, vomiting, constipation, and lower appetite, and KD may aggravate the risk of intestinal disease (Tuck & Staudacher, 2019). Notably, the biggest risk of KD is that it eliminates large amounts of carbohydrates, including some abundant unrefined carbohydrates (beans, whole grains, and fruits), which may lead to chronic ketosis (Joshi et al., 2019).
Microbiota and body weight control: Weight watchers within?
2022, Molecular MetabolismCitation Excerpt :Thus, the use of KD should be carefully regulated and monitored based on the specific medical condition and patient response. For example, concerns in the use of KD have been raised particularly for people with GI disorders or at risk of nutritional deficiency [329,330]. In addition, it was recently shown that KD aggravates cognitive impairment in mice that underwent intermittent hypoxia, by influencing the gut microbiota and by increasing intestinal IFNg-producing Th1 cells [331].
Dietary patterns affect Parkinson's disease via the microbiota-gut-brain axis
2021, Trends in Food Science and TechnologyCitation Excerpt :Notably, a recent study found that a long-term Ketogenic diet leads to obesity and impairs metabolic health in mice (Goldberg et al., 2020). Additionally, 30–50% of those who follow the Ketogenic diet suffered from side effects, including nausea, vomiting, constipation, reduced appetite, and the risk of intestinal disease (Tuck & Staudacher, 2019). Further studies are required to investigate whether the Ketogenic diet only improves PD symptoms in the short term or whether the effects are longer lasting.
Ketogenic diets: A systematic review of current scientific evidence and possible applicability in dogs and cats
2024, Journal of Animal Physiology and Animal NutritionKetone Body Metabolism and Renal Diseases
2023, Journal of Sichuan University (Medical Science)Ketogenic vs plantogenic diets for health: a review article
2023, Nutrition and Food Science