Abstract
Background
The ICEpop CAPability measure for Adults (ICECAP-A) is a measure of capability wellbeing developed for use in economic evaluations. It was designed to overcome perceived limitations associated with existing preference-based instruments, where the explicit focus on health-related aspects of quality of life may result in the failure to capture fully the broader benefits of interventions and treatments that go beyond health. The aim of this study was to investigate the extent to which preference-based health-related quality of life (HRQoL) instruments are able to capture aspects of capability wellbeing, as measured by the ICECAP-A.
Methods
Using data from the Multi Instrument Comparison project, pairwise exploratory factor analyses were conducted to compare the ICECAP-A with five preference-based HRQoL instruments [15D, Assessment of Quality of Life 8-dimension (AQoL-8D), EQ-5D-5L, Health Utilities Index Mark 3 (HUI-3), and SF-6D].
Results
Data from 6756 individuals were used in the analyses. The ICECAP-A provides information above that garnered from most commonly used preference-based HRQoL instruments. The exception was the AQoL-8D; more common factors were identified between the ICECAP-A and AQoL-8D compared with the other pairwise analyses.
Conclusion
Further investigations are needed to explore the extent and potential implications of ‘double counting’ when applying the ICECAP-A alongside health-related preference-based instruments.
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Acknowledgements
We thank Dr. Helen McTaggart-Cowan for her discussion of our paper at the 6th Vancouver Health Economics Methodology (VanHEM) meeting, Dr. Mark Oppe for his discussion at the 33rd EuroQol Group Plenary Meeting, and two anonymous reviewers for their constructive comments. This study is a secondary analysis using data from the Multi Instrument Comparison (MIC) project. None of the authors are investigators on the MIC project. For details of the MIC project, including the process for data requests, see http://www.aqol.com.au/index.php/aqol-current (accessed 28 January, 2017).
Authors’ contributions
LE, DM, SB, and DGTW were involved in the conception of the research question and design of the study. LE performed data analyses and drafted the original manuscript. All authors were involved in the interpretation of results and the review of the draft manuscript, and read and approved the final version prior to submission.
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This work has been conducted without financial support.
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SB and DGTW are members of the EuroQol Group. The authors report no further conflicts of interest.
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Engel, L., Mortimer, D., Bryan, S. et al. An Investigation of the Overlap Between the ICECAP-A and Five Preference-Based Health-Related Quality of Life Instruments. PharmacoEconomics 35, 741–753 (2017). https://doi.org/10.1007/s40273-017-0491-7
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DOI: https://doi.org/10.1007/s40273-017-0491-7