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The course of anxiety, depression and unmet needs in survivors of diffuse large B cell lymphoma and multiple myeloma in the early survivorship period

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Abstract

Purpose

The purpose of the study is to examine the course of anxiety, depression and unmet needs in diffuse large B cell lymphoma (DLBCL) and multiple myeloma (MM) survivors in the first 2 years post diagnosis.

Methods

DLBCL and MM survivors, recruited through the Victorian Cancer Registry, completed two interviews approximately 7 and 15 months post diagnosis. Hospital Anxiety and Depression Scale (HADS) and Supportive Care Needs Survey (SCNS-SF34) were completed at both interviews. Primary outcomes were prevalence of anxiety, depression and unmet needs (any or moderate–high). Generalized estimating equation examined whether course of anxiety, depression and unmet needs differed between the two cancers.

Results

Overall, 236 DLBCL and 178 MM survivors completed both telephone interviews. Course of anxiety differed (p < 0.01) with rate increasing in DLBCL (14 to 22%) while remaining stable for MM (15 to 12%). Course of depression also differed (p < 0.01), decreasing for MM (22 to 12%) and remaining stable for DLBCL (15 to 16%) survivors. Change in unmet needs was generally similar for the two cancer groups, except for moderate to high psychological needs (p < 0.05).

Conclusions

Patterns of change in anxiety and depression in first 2 years post diagnosis differ for DLBCL and MM survivors.

Implications for cancer survivors

Studying psychological outcomes in mixed haematological cancer samples may be inappropriate, at least in the early survivorship phase. Separate studies of the experiences of people with the different haematological cancer subtypes are needed to ensure psychosocial and supportive care interventions are appropriate to the needs of individuals with different haematological cancers.

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Acknowledgements

This project Improving Management by Participatory Research in Oncology—a Victorian Experiment (IMPROVE) was funded by the Victorian Cancer Agency (Translational Research Grant EOI09_36).

Author’s contribution

The research study was designed by all the authors. DO and VW analysed the data, and the following authors contributed to the writing of the paper: DO, VW, DH, MJ, SH. JS, MP, NWD and GG.

Author information

Authors and Affiliations

  1. Cancer Council Victoria, 615 St. Kilda Road, Melbourne, VIC, 3004, Australia

    Devesh Oberoi, Victoria White, David Hill & Graham Giles

  2. The University of Melbourne, Parkville, VIC, 3010, Australia

    Victoria White, John Seymour, H. Miles Prince, Simon Harrison, Michael Jefford & David Hill

  3. Peter MacCallum Cancer Centre, 305 Grattan St., Melbourne, VIC, 3000, Australia

    John Seymour, H. Miles Prince, Simon Harrison & Michael Jefford

  4. Royal Melbourne Hospital Familial Cancer Centre, Level 2, Royal Melbourne Hospital, Grattan Street, Parkville, VIC, 3052, Australia

    Ingrid Winship

  5. Austin Health, Suite 5 210 Burgundy Street, Heidelberg, VIC, 3084, Australia

    Damien Bolton

  6. North Eastern Melbourne Integrated Cancer Service, 145 Studley Rd, Heidelberg, VIC, 3084, Australia

    Anne Kay

  7. AlfredHealth, The Alfred, 55 Commercial Road, Melbourne, VIC, 3004, Australia

    Jeremy Millar

  8. Concord Hospital, Hospital Rd., Concord, NSW, 2139, Australia

    Nicole Wong Doo

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  1. Devesh Oberoi
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Correspondence to Victoria White.

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Oberoi, D., White, V., Seymour, J. et al. The course of anxiety, depression and unmet needs in survivors of diffuse large B cell lymphoma and multiple myeloma in the early survivorship period. J Cancer Surviv 11, 329–338 (2017). https://doi.org/10.1007/s11764-016-0591-y

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