Skip to main content
Log in

Pharmaceutical Research Enabled Through Microgravity: Perspectives on the Use of the International Space Station U.S. National Laboratory

  • Commentary
  • Published:
Pharmaceutical Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. International Space Station Benefits for Humanity 3rd Edition 2019. Available from https://www.nasa.gov/mission_pages/station/research/news/b4h-3rd-ed-book. Accessed 25 Aug 2019.

  2. Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, et al. The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science. 2019;364(6436):1-20.

  3. Ronca AE, Lowe MG. Rodents as a model for research in space. In: Pathak Y, Araújo dos Santos M, Zea L, editors. Handbook of space pharmaceuticals. Cham: Springer; 2019.

    Google Scholar 

  4. Beheshti A, Shirazi-Fard Y, Choi S, Berrios D, Gebre SG, Galazka JM, et al. Exploring the effects of spaceflight on mouse physiology using the open access NASA GeneLab platform. J Vis Exp. 2019;(143):e58447. https://doi.org/10.3791/58447.

  5. Low LA, Tagle DA. Tissue chips - innovative tools for drug development and disease modeling. Lab Chip. 2017;17(18):3026–36.

    Article  CAS  Google Scholar 

  6. Aleshcheva G, Bauer J, Hemmersbach R, Slumstrup L, Wehland M, Infanger M, et al. Scaffold-free tissue formation under real and simulated microgravity conditions. Basic Clin Pharmacol Toxicol. 2016;119(Suppl 3):26–33.

    Article  CAS  Google Scholar 

  7. Becker JL, Souza GR. Using space-based investigations to inform cancer research on Earth. Nat Rev Cancer. 2013;13(5):315–27.

    Article  CAS  Google Scholar 

  8. Krüger M, Melnik D, Kopp S, Buken C, Sahana J, Bauer J, et al. Fighting thyroid cancer with microgravity research. Int J Mol Sci. 2019;20(10):2553.

    Article  Google Scholar 

  9. Grimm D, Egli M, Krüger M, Riwaldt S, Corydon TJ, Kopp S, et al. Tissue Engineering under microgravity conditions-use of stem cells and specialized cells. Stem Cells Dev. 2018;27(12):787–804.

    Article  Google Scholar 

  10. McPherson A, DeLucas LJ. Microgravity protein crystallization. NPJ Microgravity. 2015;1:15010.

    Article  Google Scholar 

  11. For more information on the capabilities available through the ISS National Laboratory and how to access them visit www.issnationallab.org. Accessed 25 Aug 2019.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marc A. Giulianotti.

Additional information

Guest Editors: Sara Eyal and Hartmut Derendort

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Giulianotti, M.A., Low, L.A. Pharmaceutical Research Enabled Through Microgravity: Perspectives on the Use of the International Space Station U.S. National Laboratory. Pharm Res 37, 1 (2020). https://doi.org/10.1007/s11095-019-2719-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11095-019-2719-z

Keywords

Navigation