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Springer Handbook of Marine Biotechnology pp 1043–1057Cite as

Omega-3 Fatty Acids Produced from Microalgae

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Part of the book series: Springer Handbooks ((SHB))

Abstract

The applications of Omega-3 fatty acids for human health are rapidly expanding, which necessitates exploring alternative sources to fish. Many marine microorganisms across different kingdoms exhibit the ability to store a significant oil content, however are difficult to cultivate. Out of all marine microbes, thraustochytrids are considered a good source for the production of high value compounds such as polyunsaturated fatty acids (GlossaryTerm

PUFA

s). Optimization of culture conditions will be helpful in further enhancing cellular lipid content to suit fatty acid synthesis. This chapter describes some recent advances in the development of marine microbes for fatty acid production with a special emphasis upon thraustochytrids for biotechnological applications, focussing particularly on methods to enhanced docosahexaenoic acid (GlossaryTerm

DHA

) and eicosapentaenoic acid (GlossaryTerm

EPA

) production.

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Abbreviations

AA:

arachidonic acid

ALA:

α-linolenic acid

ARA:

arachidonic acid

ASW:

artificial seawater

AfDD:

acriflavine direct detection

CAF:

chlorophyll autofluorescence

CV:

cardiovascular

DHA:

docosahexaenoic acid

DH:

dehydratase

DO:

dissolved oxygen

EPA:

eicosapentaenoic acid

NADPH:

nicotinamide adenine dinucleotide phosphate

NTG:

N-methyl- N ′ -nitro-N-nitroso guanidine

PKS:

polyketide synthase

PUFA:

polyunsaturated fatty acid

TFA:

total fatty acid

VLC:

very long-chain

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Authors and Affiliations

  1. Centre for Chemistry and Biotechnology, Deakin University, 76 Pigdons Road, 3217, Geelong, Australia

    Munish Puri

  2. Centre for Chemistry and Biotechnology, LES, Deakin University, 75 Pigdons Road, Waurn Ponds, Victoria, 3217, Australia

    Tamilselvi Thyagarajan, Adarsha Gupta & Colin J. Barrow

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  1. Munish Puri
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  2. Tamilselvi Thyagarajan
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  1. Department of Marine-Bio. Convergence Science Specialized Graduate School Science & Technology Convergence Marine Bioprocess Research Center, Pukyong National University, Yongdang Campus, 365, Sinseon-ro, Nam-gu, 608-739, Busan, Korea

    Se-Kwon Kim Prof.

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Puri, M., Thyagarajan, T., Gupta, A., Barrow, C.J. (2015). Omega-3 Fatty Acids Produced from Microalgae. In: Kim, SK. (eds) Springer Handbook of Marine Biotechnology. Springer Handbooks. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-53971-8_45

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