Overview
- Divided into four convenient parts, highlighting the life cycle of GPCRs
- Features detailed methodologies for the characterization of GPCRs in a variety of research areas
- Includes hints at the future directions of the key areas of study in this fast-moving field
Part of the book series: Neuromethods (NM, volume 60)
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Table of contents (20 protocols)
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Front Matter
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The G Protein-Coupled Receptor in the Genome
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Front Matter
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The Trafficking of G Protein-Coupled Receptors
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Front Matter
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The G Protein-Coupled Receptor on the Membrane
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Front Matter
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The Regulation of G Protein-Coupled Receptors
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Front Matter
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Keywords
About this book
The goal of the characterization and discovery of G protein-coupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies. In Methods for the Discovery and Characterization of G Protein-Coupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the reader’s particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors. Chapters also feature an important section called “Future Directions” which gives the reader an insight into advances soon to be realized in each area. Written for the popular Neuromethods series, this book contains the kind of detailed description and implementation advice that is crucial for getting optimal results.
Authoritative and cutting-edge, Methods for the Discovery and Characterization of G Protein-Coupled Receptors serves as an ideal guide for scientists determined to further our knowledge of crucially important set of receptors.
Reviews
From the reviews:
“Methods for the Discovery and Characterization of G Protein-Coupled Receptors is an excellent reference text for anyone concerned with the dynamic life of GPCRs in living tissues. The book is suitably organized to cater to a wide audience, and the material is presented in a logical framework to permit understanding of major concepts by a novice. … This would be a particularly valuable book for any structural biologist looking to build complexity into their experimental system to account for in vivo phenomena.” (Michelle O’Malley, ChemBioChem, Vol. 13 (6), April, 2012)
Editors and Affiliations
Bibliographic Information
Book Title: Methods for the Discovery and Characterization of G Protein-Coupled Receptors
Editors: Craig W. Stevens
Series Title: Neuromethods
DOI: https://doi.org/10.1007/978-1-61779-179-6
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-178-9Published: 15 July 2011
Softcover ISBN: 978-1-4939-5851-1Published: 23 August 2016
eBook ISBN: 978-1-61779-179-6Published: 15 July 2011
Series ISSN: 0893-2336
Series E-ISSN: 1940-6045
Edition Number: 1
Number of Pages: XIII, 428
Topics: Neurosciences, Human Genetics