Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1490)
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Table of contents (17 protocols)
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Front Matter
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Back Matter
About this book
This volume provides protocols and procedures for determining and modeling RNA structure. Chapters guide the reader through protocols for RNA secondary structure prediction, single sequence modeling, Crumple, RNAstructure to model conserved secondary structures with multiple homologs, the prediction of bimolecular secondary structures with RNAstructure, STarMir, protocols for structure mapping, mapping data to constrain or restrain RNA secondary structure prediction with RNAstructure, unassigned NMR resonances, modeling protocols for Rosetta FARFAR, RNAComposer , ModeRNA, and MC-Fold. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and Practical, RNA Structure Determination:Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
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Department of Chemistry and Center for RNA Biology, University of Rochester College of Arts and Sciences, Rochester, USA
Douglas H. Turner
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Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester Medical Center, Rochester, USA
David H. Mathews
Bibliographic Information
Book Title: RNA Structure Determination
Book Subtitle: Methods and Protocols
Editors: Douglas H. Turner, David H. Mathews
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6433-8
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2016
Hardcover ISBN: 978-1-4939-6431-4Published: 24 September 2016
Softcover ISBN: 978-1-4939-8198-4Published: 27 June 2018
eBook ISBN: 978-1-4939-6433-8Published: 24 September 2016
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 283
Number of Illustrations: 15 b/w illustrations, 66 illustrations in colour
Topics: Human Genetics