Overview
- Includes cutting-edge methods and protocols in mouse genetic research
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1194)
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Table of contents(26 protocols)
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Mouse Genetics Techniques
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Mouse Genetics in Stem Cells
About this book
Mouse Genetics: Methods and Protocols provide selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages and modeling human diseases. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls.
Comprehensive and authoritative, Mouse Genetics: Methods and Protocols promises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.
Editors and Affiliations
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Stem Cell Regulation and Animal Aging Section, Basic Research Laboratory,, National Cancer Institute, National Institutes of Health, Frederick, USA
Shree Ram Singh
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Genetically Engineered Mouse Modeling Core/Department of Molecular Virology, Immunology and Medical Genetics, Wexner Medical Center, Comprehensive Cancer Center, The Ohio State University, Columbus, USA
Vincenzo Coppola
Bibliographic Information
Book Title: Mouse Genetics
Book Subtitle: Methods and Protocols
Editors: Shree Ram Singh, Vincenzo Coppola
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-1215-5
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2014
Hardcover ISBN: 978-1-4939-1214-8
Softcover ISBN: 978-1-4939-4567-2
eBook ISBN: 978-1-4939-1215-5
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 475
Number of Illustrations: 24 b/w illustrations, 68 illustrations in colour
Topics: Human Genetics, Animal Genetics and Genomics, Animal Models