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A High Content Screening Approach to Identify Molecules Neuroprotective for Photoreceptor Cells

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Retinal Degenerative Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 801))

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Abbreviations

DMSO:

Dimethyl sulfoxide

ER:

Endoplasmic reticulum

GFP:

Green fluorescent protein

HCA:

High content analysis

qHTS:

Quantitative high throughput screening

PBS:

Phosphate buffered saline

PR:

Photoreceptor

RP:

Retinitis pigmentosa

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Acknowledgment

We thank John Wilson and Ted Wensel (Baylor College of Medicine) for generously providing Rho-GFP mice, and Patricia Dranchak, Sam Hasson, and Ryan MacArthur of the NIH NCATS DPI for their help and assistance. This work was funded by an FFB/Wynn-Gund Translational Research Acceleration Program Award.

Author information

Authors and Affiliations

  1. Wilmer Eye Institute, Johns Hopkins University School of Medicine, 400 N Broadway, 21231, Baltimore, MD, USA

    John A. Fuller, Gillian C. Shaw, Delphine Bonnet-Wersinger, Baranda S. Hansen, Cynthia A. Berlinicke & Donald J. Zack

  2. National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA

    James Inglese

  3. National Human Genome Institute, NIH, Bethesda, MD, USA

    James Inglese

  4. Departments of Molecular Biology and Genetics, Neuroscience, and Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Donald J. Zack

  5. Institut de la Vision, 75012, Paris, France

    Donald J. Zack

Authors
  1. John A. Fuller
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  2. Gillian C. Shaw
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  3. Delphine Bonnet-Wersinger
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  4. Baranda S. Hansen
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  5. Cynthia A. Berlinicke
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  6. James Inglese
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  7. Donald J. Zack
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Corresponding author

Correspondence to John A. Fuller .

Editor information

Editors and Affiliations

  1. Department of Ophthalmology, University of Florida, Gainesville, Florida, USA

    John D. Ash

  2. University Hospital Zurich, Zurich, Switzerland

    Christian Grimm

  3. Cole Eye Institute at the Cleveland Clin Division of Ophthalmology, Cleveland, Ohio, USA

    Joe G. Hollyfield

  4. Dean A. McGee Eye Inst., University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA

    Robert E. Anderson

  5. Beckman Vision Center, University of California, San Francisco School of Medicine, San Francisco, California, USA

    Matthew M. LaVail

  6. Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA

    Catherine Bowes Rickman

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Fuller, J. et al. (2014). A High Content Screening Approach to Identify Molecules Neuroprotective for Photoreceptor Cells. In: Ash, J., Grimm, C., Hollyfield, J., Anderson, R., LaVail, M., Bowes Rickman, C. (eds) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, vol 801. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3209-8_97

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  • DOI: https://doi.org/10.1007/978-1-4614-3209-8_97

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-3208-1

  • Online ISBN: 978-1-4614-3209-8

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