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New Sources in Living Kidney Donation

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Kidney Transplantation: A Guide to the Care of Kidney Transplant Recipients

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Abstract

The first successful living kidney transplantation occurred in 1954 when Ronald Herrick donated a kidney to his identical twin brother, Richard, at the Peter Bent Brigham Hospital in Boston, Massachusetts. There was no possibility of a rejection of the kidney because the brothers were genetically identical twins. Since then, however, the field of kidney transplantation has evolved so that genetic identity or matching is no longer a necessary criterion for success. Advances in immunosuppressive drugs (and changes in attitudes toward non-directed living donation) currently allow successful kidney transplantation between donors and recipients even with a complete human leukocyte antigen (HLA) mismatch. Despite these advances, the risk of hyperacute rejection has prohibited kidney donation and transplantation between ABO blood type incompatible donors and renal transplant candidates.

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Acknowledgments

We thank Dr. Kenneth Andreoni, Chair of the OPTN/UNOS Kidney Paired Donation Work Group Committee, and Elizabeth F. Sleeman MHA, UNOS Policy Analyst, for their valuable assistance and insightful comments.

Author information

Authors and Affiliations

  1. New England Organ Bank, New England Program for Kidney Exchange, Organ Procurement Organization, Newton, MA, USA

    Ruthanne L. Hanto RN, MPH

  2. Department of Economics, Harvard Business School, Harvard University, Boston, MA, USA

    Alvin E. Roth PhD

  3. Department of Economics, Boston College, Chestnut Hill, MA, USA

    M. Utku Ünver PhD

  4. The Transplantation Society, World Health Organization, Massachusetts General Hospital Transplant Center, Newton, MA, USA

    Francis L. Delmonico MD

Authors
  1. Ruthanne L. Hanto RN, MPH
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  2. Alvin E. Roth PhD
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  3. M. Utku Ünver PhD
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  4. Francis L. Delmonico MD
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Corresponding author

Correspondence to Ruthanne L. Hanto RN, MPH .

Editor information

Editors and Affiliations

  1. Scripps Research Institute, N.Torrey Pines Rd. 10550, La Jolla, 92037, USA

    Dianne B. McKay

  2. Division of Transplantation, Sharp Memorial Hospital, Frost Street 7910, San Diego, 92123, USA

    Steven M. Steinberg

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© 2010 Springer-Verlag US

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Hanto, R.L., Roth, A.E., Ünver, M.U., Delmonico, F.L. (2010). New Sources in Living Kidney Donation. In: McKay, D., Steinberg, S. (eds) Kidney Transplantation: A Guide to the Care of Kidney Transplant Recipients. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1690-7_8

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  • DOI: https://doi.org/10.1007/978-1-4419-1690-7_8

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  • Print ISBN: 978-1-4419-1689-1

  • Online ISBN: 978-1-4419-1690-7

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